Tag Archives: extracellular vesicles

MicroRNA and mRNA cargo of extracellular vesicles

Mesenchymal stromal/stem cells (MSCs) are clinically useful for cell-based therapy, but concerns regarding their ability to replicate limit their human application. MSCs release extracellular vesicles (EVs) that mediate at least in part the paracrine effects of the parental cells. To ...

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Extracellular vesicles as emerging intercellular communicasomes

exosome rna

All living cells on earth release extracellular vesicles having pleiotropic functions in intercellular communication into the surroundings. Mammalian extracellular vesicles, also known as exosomes and microvesicles, are spherical bilayered proteolipids composed of various bioactive molecules, including RNAs, DNAs, proteins, and ...

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Extracellular vesicles as drug delivery systems

exosome rna

Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell contact and the secretion of soluble factors, EVs function as another mechanism of intercellular communication. ...

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