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Tag Archives: AAV vectors

Extracellular vesicles improve gene transfer with adeno-associated virus vectors

August 16, 2017 Leave a comment 1,810 Views

exosomes

Gene therapy, the ability to treat a disease at the level of nucleic acid, has journeyed from science fiction, to hard lessons learned from early clinical trials, to improved technologies with efficacy in patients for several diseases. Adeno-associated virus (AAV) ...

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Recent Exosome Pubs

Exosomes derived from normal human bronchial epithelial cells down-regulate proliferation and migration of hydroquinone-transformed malignant recipient cells via up-regulating PTEN expression.
Circular RNA circ-RanGAP1 regulates VEGFA expression by targeting miR-877-3p to facilitate gastric cancer invasion and metastasis.
Circulating exosome-derived bona fide long non-coding RNAs predicting the occurrence and metastasis of hepatocellular carcinoma.
Effects of Lyophilization of Arginine-rich Cell-penetrating Peptide-modified Extracellular Vesicles on Intracellular Delivery.
Clinical significance of hsa_circ_0000419 in gastric cancer screening and prognosis estimation.
Inhibition of miR-214-3p Aids in Preventing Epithelial Ovarian Cancer Malignancy by Increasing the Expression of LHX6.

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What is Exosome RNA?

Exosomes are cell-derived vesicles that are present in many and perhaps all biological fluids, including blood, urine, and cultured medium of cell cultures. Exosomes contain various molecular constituents of their cell of origin, including proteins and RNA. It is becoming increasingly clear that exosomes have specialized functions and play a key role in, for example, coagulation, intercellular signaling, and waste management. - from wikipedia

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The Scientist - Théry (2011)

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  • exosomes

    Exosomes may be key to diagnosing and treating nocturnal hypertension

    3 days ago
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    Exosomes and super-resolution microscopy

    3 days ago
  • exosomes

    Multilegged Exosomal Walker for Electrochemical Detection of Exosomes

    4 days ago
  • exosomes

    Generation, Purification and Engineering of Extracellular Vesicles and Their Biomedical Applications.

    4 days ago
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    Extracellular vesicle cargo can differ by race and sex and is associated with mortality risk factors

    5 days ago
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    Fluxion Biosciences Receives Foundational Patent Covering NGS Liquid Biopsy Approach

    5 days ago

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