Featured Exosome Job – Scientist, Exosome Biology

Job ID R0004790
Date posted 10/15/2018
Location: Fujisawa, Japan

Job Description

[Introduction of Takeda]

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Scientist, Exosome Biology in our Shonan Health Innovation Park.

Takeda is a global pharmaceutical leader with more than 30,000 professionals working together. We have an unwavering dedication to put people first and we live our values of Takeda-ism: Integrity, Fairness, Honesty, and Perseverance. We are united by our more than 230-year legacy of research-based pharmaceuticals and our mission to strive toward Better Health and a Brighter Future for people worldwide through leading innovation in medicine.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own.

タケダでは、常に患者さんを中心に考え、その生活を豊かにするためにイノベーションを推進しています。そして、従業員一人ひとりにそれぞれの能力と熱意に応じた成長の機会を提供することにも組んで取り組んでいます。私たちと一緒に、世界中の人々のいのちに貢献し、さらなる成長と活躍を目指しませんか。

タケダは2万7千人以上の従業員が、54以上の国や地域で働くグローバルな企業です。すべての従業員が世界中の人々の生活をより良いものにしたいという信念をもち、そしてタケダイズム(誠実:公正・正直・不屈)を日々の業務で体現しています。私たちは、237年の研究開発型の製薬企業としての伝統のもと団結し、優れた医薬品の創出を通じて、人々の健康と医療の未来に貢献することをミッションとして掲げています。

[Group/ Function’s Goal]

Heterogeneity of CNS disorders is one of the major barriers for drug discovery. Analysis of exosome in patient specimen, such as plasma and CSF, is one of the key approach to overcome the difficulty. The group responsibility is to discover novel patient stratification biomarkers by exosome analysis, molecular pathological analysis, and cutting edge technologies. Also the group responsibility is to clarify drug target molecules and the mechanism for neuroscience therapeutic area drug projects by using multi-omics data such as chemical proteomics, metabolomics and transcriptomics.

[Accountabilities]

  • Plans and executes cutting edge exosome assay development including exosome isolation, preparation and analysis using biological samples including human plasma, CSF and tissue.
  • Collaborates with drug discovery project members to be responsible for evaluating drug mechanisms through exosomal-omics analyses.
  • Handles comprehensive cross-omics data to understand biological and pathogenic pathways by bioinformatics approach.
  • Writes research reports and academic papers timely and communicates effectively with internal and external partners.

[Requirements]

Required:

  • PhD or equivalent in science with molecular biology, cell biology or related field
  • Minimum 3 years experience in biological experiments of exosome, extracellular vesicle or related field
  • Experience in biomarker experiments using human biological samples including blood, CSF and tissue
  • Deep understanding of biological pathway analysis from bioinformatics approach.
  • Good communication skills and proactive mindset to effectively drive collaborative researches forward with internal and external partners
  • Good written and verbal communication skills in Japanese and/or English
  • Results driven mindset

Preferred:

  • Knowledge and expertise in CNS diseases drug discovery (strongly preferred)
  • Knowledge and experience in Bioinformatics and Systems Biology (strongly preferred)
  • Demonstrated experience in Multi-omics (transcriptomics, proteomics, genomics, metabolomics)
  • Familiar with RNA sequencing technologies

[Employee Benefits]

  • Allowances: Commutation, Housing, Overtime Work etc.
  • Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/Yamaguchi) 8:00-16:45, Research Site (Kanagawa) 9:00-17:45
  • Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
  • Paid Leaves: Annual Paid Leave, Special Paid Leave, Refresh Leave, Maternity Leave, Childcare Leave, Family Nursing Leave, Philanthropy Leave.
[待遇]
  • 諸手当:通勤交通費、借家補助費、勤務時間外手当など
  • 昇給:原則年1回
  • 賞与: 原則年2回
  • 勤務時間:本社(大阪市中央区・東京都中央区)9:00~17:30 、工場(山口県光市・大阪市淀川区)8:00~16:45 、研究所(神奈川県藤沢市)9:00~17:45
  • 休日:土曜、日曜、祝日、メーデー、年末年始など(年間123日程度)
  • 働き方関連制度:フレックスタイム制、テレワーク勤務制導入(対象社員)
  • 休暇:年次有給休暇、特別有給休暇、リフレッシュ休暇、産前産後休暇、育児休暇、
  • 子の看護休暇、介護休暇、フィランソロピー休職制度
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