This position will provide technical support in a laboratory in the Neuroimmunology and Neurological Infections Division, Department of Neurology focused on neurological disorders, such as Alzheimer’s disease. The position is in a disease-oriented research group that addresses questions in basic neurobiology. The primary interests are: 1) to use extracellular vesicles/exosomes derived from human iPSCs and iPSC-derived neurons as tools for biomarker discovery and therapeutic applications. 2) To generate a better understanding at the molecular and cellular level of the contributions of extracellular vesicles to Alzheimer’s. 3) To develop 3D systems as novel platforms to study Alzheimer’s Disease. The person will be responsible for experiments related to multiple ongoing studies.
Specific duties & responsibilities:
Under initial supervision of the faculty investigator and lab research personnel, the research technologist performs tissue culture and molecular biology experiments. The technologist will have independent projects and may be included as a co-author of publications resulting from his or her work in the laboratory. Specific techniques used include cell and tissue culture, PCR, DNA extraction and analysis, gel electrophoresis, flow cytometry and immunostaining. Applicants must be familiar with the operation of basic laboratory equipment and with sterile technique. In consultation with a supervisor, an experienced technologist will perform, evaluate and troubleshoot methods as necessary, prepare solutions and reagents following standard procedures and keep an organized lab notebook. Meet at least weekly with principal investigator to report on research and laboratory status.
Minimum qualifications (mandatory):
Bachelor’s degree in biology, chemistry, or related field required. Some related post-undergraduate work experience preferred.
The successful candidate will be enthusiastic, energetic and reliable. Interest in learning a multitude of diverse techniques and flexibility regarding projects and protocols is important. Familiarity with technical aspects of molecular biology practices and relevant biological and biochemical theory is essential. Experience in culture human pluripotent stem cells such as ES and iPS cells is a plus.
Special knowledge, skills, and abilities:
Computer or other special needs for the position: Able to efficiently use Microsoft Office programs: Excel, Word and PowerPoint. Ability to learn new computer skills and applications quickly including how to install software, firmware, and manipulate hardware/peripherals
Must be able to efficiently and proactively communicate with supervisors and coworkers, manipulate small and large test tubes, flasks and pipettes, move some moderately-large equipment and boxes, type quickly, write nimbly and legibly, see very well at a short distance, communicate clearly by phone, move within the building and around campus, and work at the bench (and sometimes at a microscope with micromanipulator, etc.) for extended periods.
Title – Research Technologist
Starting Salary Range: $13.73 – $ 18.87
Employee group: Full Time
Employee subgroup: Non exempt
Schedule: Working 40 hours per week; M-F 8:30 am -5:00 pm
The successful candidate(s) for this position will be subject to a pre-employment background check.