Methods

Exosomes are nano-sized vesicles, which are currently under intensive study as potential diagnostic biomarkers for many health disorders, including cancer. Researchers from UAB Barcelona tested an electrochemical immunosensor in different formats for the characterization and quantification of exosomes derived from ...

Despite extensive interest, extracellular vesicle (EV) research remains technically challenging. One of the unexplored gaps in EV research has been the inability to characterize the spatially and functionally heterogeneous populations of EVs based on their metabolic profile. Researchers from the ...

Exosomes are a specific subpopulation of extracellular vesicles that have gained interest because of their many potential biomedical applications. However, exosome isolation and...

Exosomes represent a new generation of biomarkers for the early diagnosis of hepatic carcinoma. Researchers from Tongji Medical College have developed a fluorometric assay that is based on the hybridization chain reaction and magnetic...

Exosomes are nano-scale membrane-encapsulated vesicles produced by the majority of cells and have emerged as a rich source of biomarkers for a wide variety of diseases. Although many approaches have been developed for exosome isolation from biofluids, most of them ...

Exosomes released from cells play an important role in intercellular communication and show great clinical potential in early cancer screening and prognosis. Researchers from Shanghai Jiao Tong University have developed an ultrasensitive Giant...

Microvesicles and exosomes are promising liquid biopsy biomarkers. However, conventional isolation techniques damage and contaminate the biomarkers. Kwangwoon University researchers have developed an origami-paper-based device for...

Researchers from the Imperial College London non-covalently functionalised a graphene field-effect transistor (gFET) with 1-pyrenebutyric acid N-hydroxysuccinimide ester and conjugated with anti-CD63 antibodies for the label-free detection of...

Imaging of Extracellular Vesicles by Atomic Force Microscopy  Exosomes and other extracellular vesicles (EVs) are molecular complexes consisting of a lipid membrane vesicle, its surface decoration by membrane proteins and other molecules, and diverse luminal content inherited from a parent ...

Exosomes are one class of extracellular vesicles (30-150 nm diameter) that are secreted by cells. These small vesicles hold a great deal of promise in disease diagnostics, as they display the same protein...