Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor...

Biodesix, Inc, the leader in blood-based lung cancer diagnostic solutions, today announced it has entered into an agreement with Thermo Fisher Scientific. The agreement is designed to bring a blood-based next-generation sequencing (NGS) assay to market...

Extracellular vesicles (EVs) are intercellular communicators with key functions in physiological and pathological processes and have recently garnered interest because of their diagnostic and...

MicroRNAs (miRNAs), particularly those found in human body fluids, have been suggested as potential biomarkers. Among various body fluids, the cerebrospinal fluid (CSF) shows promise as a profiling target for diagnosis and monitoring of neurological diseases. However, relevant genome-scale studies ...

Sequencing genetic material from liquid biopsies promises to be one of the most important recent developments in cancer diagnostics. The relative ease and minimally invasive nature of obtaining liquid biopsies makes it an attractive alternative source of tumor DNA relative ...

The ability to perform comprehensive profiling of cancers at high-resolution is essential for precision medicine. Liquid biopsies using shed exosomes provide high-quality nucleic acids to obtain molecular characterization, which may be especially useful for visceral cancers that are not amenable ...

Exosomes are nanosized (30-100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes. Because ...

Numerous noninvasive methods are currently being used to determine biomarkers for diseases such as cancer. However, these methods are not always precise and reliable. Thus, there is an unmet need for better diagnostic and prognostic biomarkers that will be used ...

A study by researchers from Hackensack Meridian John Theurer Cancer Center — part of the Georgetown Lombardi Comprehensive Cancer Center, an NCI...

CD Genomics, a USA-based genetic sequencing company and an expert in transcriptomics and next generation sequencing, has released its newly-developed exosomal RNA sequencing service to customers...