Monthly Archives: February 2014

Microvesicles and exosomes for intracardiac communication

exosome rna

The heart is an organ with a complex mixture of well-organized interactions of different cell types that facilitate proper myocardial contractility, sufficient perfusion, balanced myocardial extracellular stiffness, and controlled functioning of the immune system. Several cell types, including cardiomyocytes, endothelial ...

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The proteomics of prostate cancer exosomes

Exosomes and other microvesicles are emerging as rich reservoirs of tumor-specific proteins and biomarkers for cancer detection and progression. For prostate cancer, exosomes secreted by the prostate can be isolated from prostatic secretions, seminal fluid, tissue, urine or blood for ...

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Exosomes & Single Cell Analysis Summit

exosome rna

18-19 September 2014, San Diego, USA The Exosomes and Single Cell Analysis Summit 2014 features the most up-to-date topics in this expanding field and brings together an array of leading international speakers–the only event in its class, this conference aims ...

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MiRNA in melanoma-derived exosomes

exosome rna

Proteins, RNAs and viruses can be spread through exosomes, therefore transport utilizing these nanovesicles is of the great interest. MiRNAs are common exosomal constituents capable of influencing expression of a variety of target genes. MiRNA signatures of exosomes are unique ...

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The potential of exosomes in diagnosis and treatment

exosome rna

Extracellular vesicles, in particular exosomes, have gained much attention as potent mediators of intercellular signaling. Exosomes are 50-130 nm intraluminal vesicles of multivesicular bodies (MVB) that are secreted into the extracellular environment upon fusion of MVB with the plasma membrane. ...

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