Post-doc Position Available – Research Scientist in Exosome Biology and Therapeutics

Department of Physiology, Anatomy and Genetics, Oxford

Grade 7: Salary in the range £31,076 – £33,943 p.a.

Applications are sought for a full-time Postdoctoral Research Scientist to be based in the Department of Physiology, Anatomy and Genetics, Oxford. The successful applicant will join a highly active research team and will be funded by a grant from Evox Therapeutics. The research team is directed by Professor Matthew Wood. The Wood Group has been developing an exosome-based therapeutic platform technology for the last 8 years. We have developed exosome technology for the delivery of RNA based drugs and in parallel have developed a range of technologies to modify the protein composition of exosomes and to permit the targeting of exosomes to particular tissue compartments, most notably to the brain via the expression of targeting proteins such as the Rabies virus glycoprotein. This project is part of a larger cohort of projects aimed at improving the efficiency of extracellular vesicles as vehicles/modulators of therapy, funded by the recent Wood laboratory spin out company, Evox Therapeutics. The Wood laboratory and the University Unit in the Department of Physiology, Anatomy and Genetics provide an excellent state-of-the-art internationally recognised environment for work investigating and engineering extracellular vesicles as a means of novel molecular therapies for neuropathologies.

The postholder will drive all cellular, exosome engineering and RNA loading optimisation research (incl. exosome isolation, in vitro biochemical and biophysical characterisation assays). The position is an excellent opportunity for a highly ambitious, motivated and innovative scientist to expand their skill-set, with additional training in state-of-the art methods for the study of exosome biology while using advanced therapeutic approaches.

We are very strongly interested in the postholder bringing new technical expertise from relevant fields including, but not limited to, gene therapy, nanoparticle-RNA interaction, and pharmaco-kinetic/–dynamic analyses.

Candidates must have a PhD or equivalent in any area of biological science with experience in the field of exosome research and/or gene therapy/nanotechnology. Exceptional levels of motivation, innovation and a highly collaborative personality are required to lead this ambitious project along with the ability to work both independently and as part of a research team.

The post is funded until 4 July 2018 in the first instance and will be based in the Le Gros Clark building, South Parks Road, Oxford, OX1 3QX.

The closing date for applications is 12.00 noon on 17 July 2017.

Contact Person : HR Administrator Vacancy ID : 129429
Contact Phone : 01865 282669 Closing Date : 17-Jul-2017
Contact Email : hr@dpag.ox.ac.uk

 

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