San Francisco, CA | Translational Medicine
This position will be responsible for biomarker discovery and diagnostic development for rucaparib and other Clovis programs. This positon will work effectively with Translational Medicine, Biostatistics, Clinical Development, Regulatory, Clinical Operation, and Commercial functions to lead the preparation and implementation of biomarker plans within clinical studies. He/she will analyze and interpret study data, and prepare reports for internal submission and publication. The ability to develop and manage strategic collaborations with key third parties including academic and commercial vendors is an important element of the role. The position will need to communicate to project team and executive committee level.
The key tasks will initially include (at least) the following:
- Evaluation of molecular diagnostic approaches using minimally invasive blood-based matrices such as circulating tumor cells, circulating tumor DNA, and tumor-derived exosomes, for the rucaparib program
- Management of analytical and clinical validation of companion diagnostics assays
- Management of academic collaborations to support exploratory technical feasibility studies
- Assessment of new technologies and, where appropriate, new drug assets
- Writing and oral presentation of scientific data to internal and external audiences
Skills & Requirements
The ideal candidate will be a dynamic and innovative molecular diagnostics researcher with expertise in cancer biology. He or she will have the interpersonal skills required to communicate effectively with a first-rate scientific team, cross-functionally with other groups, and will play a critical role in the co-development of companion diagnostics to support the development of exciting new therapies in the treatment of cancer.
Education and Experience
- A PhD in molecular biology, bioinformatics, or related field, with at least 8 years of research experience in cancer genomics and/or molecular diagnostics is required
- Possessing expertise in cancer genomic analysis and an enthusiasm for personalized medicine, he or she will have demonstrated success in the field of oncology with an ability to leverage cutting edge technology platforms for the development of specific molecular diagnostics
The ideal candidate will have hands-on experience in molecular biology, and management of project activities including, but not limited to:
- Development of companion diagnostics
- Management and analyses of clinical trial samples
- Analytical and clinical validation procedures for companion diagnostics and experience with CDRH
- Strong organizational skills, ability to prioritize and multi-task
- Excellent verbal and written communication skills, and cross functional partnership
- Excellent publication record
- Management of research associates
Office based position with some travel required (up to 10%).