Exosomes and microvesicles as biomarkers and diagnostics

exosome rna

Exosomes and microvesicles, which are derived from the plasma membrane, contain protein, mRNA and microRNA, and play a role in intercellular communication. While exosomes are not a new discovery, recent research has indicated a wide range of applications in profiling of mRNA, microRNA and proteins in exosomes to develop new biomarkers for drug and diagnostic development. Second Annual Exosomes and Microvesicles as Biomarkers and Diagnostics will cover recent advances in the understanding of their biology, detection and profiling technologies, and their new commercial applications in drug and diagnostic development.

Preliminary Agenda

Potential of Exosomes as Biomarkers and Diagnostics

Salivary Exosome and Extracellular RNA: Biology and Translational Utilities

David T.W. Wong, D.M.D., D.MSc., Professor and Associate Dean, Research, UCLA School of Dentistry; Director, Dental Research Institute

Circulating Extracellular Vesicles as Possible New Biomarkers for Drug-Induced Liver Injury

Qiang Shi, Ph.D., Visiting Scientist, Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration

Extracellular Vesicles (EV) as a Molecular Diagnostic Platform

Clark C. Chen, M.D., Ph.D., Associate Professor and Chief, Stereotactic and Radiosurgery, Vice-Chairman, Academic Affairs, Neurosurgery, University of California, San Diego

Point-of-Care Diagnostic Technologies for Exosomal Analysis

Hakho Lee, Ph.D., Assistant Professor, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School

Non-Invasive Intracellular Kidney Biopsies: The Promise of Urine Exosomal Biomarkers

Peter Yuen, Ph.D., Staff Scientist, Renal Diagnostics & Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

 

Role of Exosomes in Cancer Mechanism

Exosomes as Mediators of JAK/Stat Activation-Regulation of Metastasis

Jacqueline Bromberg, M.D., Ph.D., Physician-Scientist, Breast Cancer, Memorial Sloan-Kettering Cancer Center

Tumor-Derived Exosomes (TEX) as Biomarkers of Human Immune Cell Dysfunction and Tumor Progression

Theresa Whiteside, Ph.D., M.D.H.C., Professor, Pathology, Immunology & Otolaryngology, University of Pittsburgh Cancer Institute

Exosomic microRNAs Affect the Biology of the Tumor Microenvironment

Muller Fabbri, M.D., Ph.D., Assistant Professor, Pediatrics and Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, Children’s Hospital Los Angeles

 

Exosomes as Disease Biomarkers

LRRK2 and Other Novel Exosome Proteins in Parkinson’s Disease

Andrew West, Ph.D., John A. and Ruth R. Jurenko Professor of Neurology, Associate Professor, Neurology and Neurobiology, Co-Director, Center for Neurodegeneration and Experimental Therapeutics, The University of Alabama at Birmingham

Novel Role of Microvesicles in Cardiovascular and Autoimmune Diseases

Ming-Lin Liu, M.D., Ph.D., Research Assistant Professor, Dermatology, Perelman School of Medicine, University of Pennsylvania

Extracellular Vesicles in Pulmonary Vascular Disease: Friend or Foe?

Jason Aliotta, M.D., Assistant Professor, Medicine, Warren Alpert Medical School, Brown University

 

Exosome Profiling for Nucleic Acid and Protein Biomarkers

Oncogenic Cargo of Extracellular Vesicles – From DNA to Active Protein

Janusz Rak M.D., Ph.D., Jack Cole Chair in Pediatric Hematology/Oncology, Professor of Pediatrics, McGill University, Montreal Children’s Hospital, RI MUHC

Redefining the Exosomal Proteome

Austin Yang, Ph.D., Associate Professor, Anatomy and Neurobiology, University of Maryland

D- and L-MARCKS-ED as Novel Exosome Probes

Hang Hubert Yin, Ph.D., Associate Professor, Chemistry & Biochemistry and the BioFrontiers Institute, University of Colorado Boulder

For more information, please contact:
Julia Boguslavsky
Executive Director, Conferences
Email:  juliab@healthtech.com

For sponsorship information, please contact:
Carolyn Benton
Manager, Business Development
Email:  cbenton@healthtech.com or Phone: 781-972-5412

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