Exosomes are nanoscale extracellular vesicles that are shed from different cells in the body. Exosomes encapsulate several biomolecules including lipids, proteins, and nucleic acids, and can therefore play a key role in cellular communication. These vesicles can be isolated from different body fluids and their small sizes make them attractive in various biomedical applications. Researchers from Arizona State University discuss state-of-the art approaches in exosome isolation and purification, and describe their potential use in cancer vaccines, drug delivery, and diagnostics.
Emerging applications of exosomes in cancer therapeutics and diagnostics
Inamdar S, Nitiyanandan R, Rege K. (2017) Emerging applications of exosomes in cancer therapeutics and diagnostics. Bioengineering and Translational Medicine [Epub ahead of print]. [article]